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Is Gleevec chemotherapy? Chemotherapy for Chronic Myeloid Leukemia. Chemotherapy (chemo) is the use of anti-cancer drugs that are injected into a vein or taken by mouth. It's seldom used now because TKIs like imatinib (Gleevec) work much better.Today, chemo may be used to treat CML when the TKIs have stopped working.
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